91ɬÂþ Seal (for official use only)
 

POLICY #6.43
SUBJECT: Care and Use of Vertebrate Animals in Research and Instruction

I. PURPOSE

The purpose of this Policy is to establish policy regarding care and management of animals used in research and instruction.

II. REFERENCES

  1. (1966)
  2. . Developed by the American Psychological Association’s Committee on Animal Research and Ethics (CARE) (2003)
  3. . The American Society of Mammalogists (ASM) (1998)
  4. . Edited by Abbot S. Gaunt & Lewis W. Oring, Special Publication of The Ornithological Council (1997)
  5. . American Society of Ichthyologists and Herpetologists (ASIH), American Fisheries Society (AFS), and American Institute of Fisheries Research Biologists (AIFRB); Fisheries
  6. . American Society of Ichthyologists and Herpetologists (ASIH), The Herpetologists' League (HL), and Society for the Study of Amphibians and Reptiles (SSAR)
  7. . National Institutes of Health, Office of Laboratory Animal Welfare

III. DEFINITIONS

N/A

IV. POLICY

  1. Applicability

    91ɬÂþ recognizes that the proper care and management of animals used in research and instruction is essential to the wellbeing of the animals, to the validity of research data, to the quality of instruction, and to the health and safety of those caring for and using animals. Therefore, this policy is applicable to all research and instruction activities conducted at or under the auspices of 91ɬÂþ that involve vertebrate animals, including non-laboratory species.
  2. General Policy
    1. It is the policy of the university that use of live vertebrate animals in research and instruction will conform to all applicable laws, rules, and regulations of the United States Government and the State of Utah. Furthermore, all such research and instruction must be performed in compliance with the highest standards of ethics, practice, and conduct of each of the fields or disciplines involved in each of the specific research projects or instructional activities.
    2. To ensure compliance with regulations regarding the humane care and use of animals in research and instruction, 91ɬÂþ’s President will appoint an Institutional Animal Care and Use Committee (IACUC) which meets regulatory requirements and is charged with the responsibility of ensuring the humane care and use of animals at the University.
    3. 91ɬÂþ and the Institutional Animal Care and Use Committee recognize the following regulatory authorities for the care and use of animals:
      1. The U.S. Department of Agriculture (USDA). The Animal Care (AC) section of the Animal and Plant Health Inspection Service (APHIS) of the USDA is responsible for implementing the regulations and standards promulgated by the Secretary of Agriculture under the mandate of the Animal Welfare Act. The regulations define institutional responsibility for assuring compliance with the Animal Welfare Act. The standards set minimal requirements for humane handling, housing, space, feeding, watering, sanitation, ventilation, exercise, and psychological well being of various species. Compliance requirements include annual reporting, application of standards for animal care and use during experimentation, documentation of the number of animals used, and summaries of exceptions granted for scientific necessity. USDA personnel perform unannounced inspections of institutional animal facilities.
      2. The (OLAW) is responsible for the general administration and coordination of National Institutes of Health (NIH) policy regarding animal care and use. Public Health Service (PHS) awarding units may not make an award for a project involving vertebrate animals unless the institution submitting the application or proposal is on the list of institutions that have an acceptable animal welfare assurance letter on file with OLAW, and the responsible institutional official has provided verification of approval by the Institutional Animal Care and Use Committee. All records that directly relate to applications, proposals, and proposed changes in ongoing research reviewed and approved by the Animal Care Committee must be maintained for at least three years after completion of the research and must be accessible to OLAW with reasonable notice.
    4. 91ɬÂþ and the Institutional Animal Care and Use Committee (IACUC) further recognize the guidelines listed in Section II, and any others, which are subsequently officially adopted by the IACUC, for the care and use of non-laboratory animals in research and instruction.
  3. Composition and Governance of the Institutional Animal Care and Use Committee (IACUC)
    1. The Institutional Animal Care and Use Committee (IACUC) will be appointed by the Provost and will advise the Provost (Institutional Official) about matters pertaining to animal care and utilization in research and instruction.
    2. The membership of the IACUC will meet the requirements of Federal regulations and will include members who are qualified through experience and expertise. The IACUC will include at least three voting members. One will be a Doctor of Veterinary Medicine with training or experience in laboratory animal science and medicine who will have responsibility for providing veterinary care to the animals. At least one (1) member of the committee will not have any affiliation with the University except service on the IACUC.
    3. Other than the attending veterinarian, who will be an ex-officio member, IACUC members are appointed for a term of three (3) years with reappointment possible.
    4. The terms of voting IACUC members will be staggered with at least one (1) member completing their term each academic year. (The academic year is August 16 to August 15.)
    5. An IACUC Chair and an IACUC Vice-Chair will each be elected for a three-year term at the first IACUC meeting of the academic year.
    6. In the event of resignation of the Chair from the position but not the committee, the Vice-Chair will assume the Chair position and will complete the departing Chair’s term of office. A new Vice-Chair will then be elected from among the voting members.
    7. In the event of resignation of the Chair from the committee, the Vice-Chair will assume the Chair position and will complete the departing Chair’s term of office. They will then identify and recommend a replacement member for appointment by the President. A new Vice-Chair will then be elected from among the voting members to complete the departing Vice-Chair’s term of office.
    8. In the event of resignation of the Vice-Chair from the position but not the committee, the Chair will hold a special election to select a new Vice-Chair from among the voting members. The new Vice-Chair will complete the original Vice-Chair’s term of office.
    9. In the event of resignation of the Vice-Chair from the committee, the Chair will identify and recommend a replacement member for appointment by the President. The Chair will then hold a special election to select a new Vice-Chair from among the voting members. The new Vice-Chair will complete the departing Vice-Chair’s term of office.
    10. In the event of resignation from the committee of a voting member who is not an officer, the Chair of the IACUC will identify and recommend a replacement for appointment by the President. The member appointed to fill the vacancy will assume the remaining term of the departing member.
    11. The Director of the Institutional Animal Care and Use Program (IACUP) will serve as a non-voting consultant to the IACUC.
    12. The Office of Sponsored Projects (OSP) will provide staff support to the IACUC by providing announcements and agendas for its meetings, recording the minutes of its meetings, serving as a repository of all IACUC correspondence and records, and the like.
    13. Office of Sponsored Projects will serve as the first and primary contact point for inquiries and submissions to the IACUC. SPO staff will forward applications to IACUC members for review.
    14. If deemed necessary by the IACUC, during the Spring semester of each year, the Director of Sponsored Projects will issue a request to the faculty for nominations to replace outgoing IACUC members. Current IACUC members may also submit nominations. Nominations will be submitted to the Office of Research and Sponsored Projects.
    15. The Director of Sponsored Projects, after consultation with the IACUC Chair, and the Director of the Institutional Animal Care and Use Program, will submit to the Provost a slate of individuals recommended to replace outgoing IACUC members. The Provost will appoint the new members.
    16. The IACUC will meet at least once per month during September, January, and May to review protocols and to tend to other business as needed. Meeting dates and protocol review application deadlines will be made public to the university at the beginning of each semester. Other meetings will be held as needed.
    17. In addition to its regular meetings, the IACUC will meet at least once every six (6) months to review the institution’s animal care and use program and to inspect the animal facilities. These meetings and inspections may be conducted immediately preceding or immediately following a regularly scheduled IACUC meeting.
    18. A simple majority of the voting members will constitute a quorum.
    19. Alternate members may be appointed by the Provost to serve and participate on the IACUC in the absence of voting members. When a quorum of voting members is not present, the IACUC Chair may delegate full responsibilities of membership (including voting privileges) to an alternate member.
    20. The IACUC may solicit ad hoc reviewers with specific expertise to assist in protocol reviews on a case-by-case basis. Ad hoc reviewers may participate, but not vote, in the designated reviews.
  4. Responsibilities of the Institutional Animal Care and Use Committee (IACUC)
    1. The Institutional Animal Care and Use Committee will conduct semi-annual reviews of the University’s Institutional Animal Care and Use Program (IACUP) and will report findings to the Provost.
    2. The IACUC will conduct semi-annual inspections of all of the University’s animal facilities, including satellite facilities, and will report findings to the Provost.
    3. The IACUC will receive and review concerns or complaints reported by faculty, staff, students, or members of the general public concerning the care and use of animals at the 91ɬÂþ.
    4. The IACUC may make written recommendations to the Provost regarding any aspect of the University’s animal care and use program, facilities, or personnel training.
    5. The IACUC will review all research and instruction protocols involving vertebrate animals conducted at, or under the auspices of, any unit of the 91ɬÂþ, whether or not supported by an external agency. The following types of projects are subject to IACUC review and approval:
      1. Externally or Internally Funded Research Proposals. Prior to submitting a grant proposal for extramural or intramural funding, or as soon thereafter as possible, the investigator must submit an Animal Care and Use Protocol Review Application (ACUPRA). No animals may be acquired for research or instruction before review and approval of the protocol by the IACUC.
      2. Independent Faculty Research or Laboratory Exercises. All independent faculty research with vertebrate animals, including pilot experiments conducted to obtain data necessary to the preparation of extramural grant proposals, and other laboratory exercises require approval of the experimental protocols and husbandry methods by the IACUC before being initiated.
      3. Field Research and Biological Surveys. All fieldwork involving vertebrate species, whether research or instruction, must be approved by the IACUC prior to initiation. Particular attention must be given to activities that may involve animals that are on the state or Federal threatened, endangered, or protected species lists, that require special permits for handling, or that involve use of equipment and procedures that may be construed by some as inhumane.
      4. Independent Student Research (excluding senior paper). Faculty members who supervise independent research projects may submit a set of procedures for approval by the IACUC from which the student may select to address the independent research question identified. Procedures not included in those approved for the class instructor and specific for the laboratory will require submission of an independent request for protocol evaluation. Students should be made aware by the faculty member that this may delay their research and may adversely affect their ability to complete the course in the prescribed time interval.
      5. Senior Paper Research. All Senior Paper research protocols involving animals, including pilot or exploratory research, must be approved by the IACUC prior to initiation of the work with animals. Student submissions must be cosigned by their major professor or advisor, who will have ultimate responsibility for proper training of the student in the care and handling of the animals and in any specialized techniques required for the research.
      6. Classroom Instruction. All classroom instruction activities involving the use of live vertebrate animals must be approved by the IACUC prior to initiation.
      7. General Animal Care and Use Protocols. The Investigator or instructor responsible for general animal care and use in any facility must submit an Animal Care and Use Protocol Review Application (ACUPRA) for these tasks. Included under this project classification are procedures for animal display facilities and animal breeding programs. These submissions must include a list of the species to be maintained and an estimate of the numbers of each animal bred or used annually. If animals maintained or produced under such an approval are transferred to an Investigator for use in experiments or to an instructor for educational purposes, the investigator or instructor must have a valid IACUC approved project for use and maintenance of the transferred animals and must notify the IACUC of the species and number of animals transferred.
    6. The use of vertebrate animals in research or instruction covered by this policy will not be permitted until the IACUC has reviewed and approved the protocol. The IACUC will not normally consider any requests for retroactive approvals.
    7. The IACUC will exercise its responsibility and authority to approve, withhold approval of, or require changes in research or instructional protocols involving vertebrate animals in accordance with Federal regulations and accepted guidelines.
    8. The IACUC will review, approve, withhold approval of, or require modifications to proposed significant changes regarding the use of vertebrate animals in previously approved research or instruction protocols.
    9. The IACUC will notify the investigator or instructor, the Office of Research and Sponsored Projects, the Department Chair/Cognizant Administrator, and the Provost in writing of decisions to approve, withhold approval of, or require modifications to those proposed protocols reviewed.
    10. The IACUC may suspend any activity involving vertebrate animals that is not being conducted in compliance with applicable provisions of Federal or state law or university policy or in accordance with a protocol approved by IACUC.
    11. The IACUC will report suspended activities or continuing or serious non-compliance with the requirements of this policy to the investigator’s/ instructor’s Department Chair and Dean and the Provost and to Federal authorities as required by the Federal Animal Welfare Act, the Public Health Service Policy on Humane Care and Use of Laboratory Animals, and to any applicable funding agency.
    12. When research or instruction involving vertebrate animals is conducted through a cooperative project at, or in cooperation with, another entity, all provisions of this policy remain in effect. The 91ɬÂþ IACUC may accept, for the purpose of meeting the IACUC review requirements, the review of an IACUC established in accordance with U.S. Department of Agriculture and U.S. Department of Health and Human Services, Public Health Service, rules and regulations. Such acceptance must be in writing and must be signed by the Chairs of the Institutional Animal Care and Use Committees at each of the cooperating institutions.
  5. Responsibilities of the Investigator/Instructor
    1. The investigator/instructor who anticipates using vertebrate animals should become knowledgeable about, and conduct all research and instruction in accordance with, approved policies governing the care and use of animals.
    2. The investigator/instructor should participate in continuing education and training programs designed to keep animal users abreast of the latest regulations and procedures. The investigator/instructor should also emphasize the role of animals in their studies when presenting research results or discussing human and animal diseases with lay audiences and should describe the contributions of humanely conducted animal studies to the development of new technologies and treatment capabilities.
    3. The investigator/instructor should maintain a scholarly, sensitive, and respectful environment during all experimentation and instructional activities involving the use of animals.
    4. The investigator seeking external funding should indicate the involvement of vertebrate animals on the University’s Office of Research and Sponsored Projects Pre-Award Proposal Routing Sheet for sponsored projects.
    5. The investigator/instructor should prepare an Animal Care and Use Protocol Review Application (ACUPRA), giving a complete description of the proposed animal care and use protocol. (Application forms are available from the Office of Research and Sponsored Projects). The investigator/instructor will make provisions for the humane care and use of the animals and will ensure that pertinent laws, regulations, and guidelines are observed.
    6. The investigator/instructor will ensure that all protocols involving vertebrate animals are submitted to the Institutional Animal Care and Use Committee through the Office of Research and Sponsored Projects and approved by the IACUC prior to initiating the proposed work.
    7. The investigator/instructor will submit a protocol modification request to the IACUC when the plans for use of vertebrate animals previously submitted will be different from that which was initially approved by the IACUC. The investigator/instructor will not initiate changes without prior IACUC review and approval, except when necessary to eliminate apparent immediate hazards to the animals or to humans.
    8. The investigator/instructor using vertebrate animals will comply with all IACUC decisions, conditions, and requirements.
    9. The investigator/instructor will maintain and use animals only in approved animal facilities whenever possible. IACUC approval is required when animal use protocols dictate unusual environmental, dietary, or colony requirements that cannot be met in approved animal care facilities.
    10. The investigator/instructor will ensure that animal care and use records are retained for a minimum of three years after animal use is completed and that they are easily accessible by U.S. Department of Agriculture inspectors and IACUC monitors. These records may not be removed from the campus without the prior approval of the IACUC.
    11. The investigator/instructor will submit continuing review applications to the IACUC as often as, and in the manner, prescribed by the IACUC, but not less than once per year, as long as the use of animals is ongoing.
    12. The investigator/instructor will report promptly to the IACUC, the Director of the Institutional Animal Care and Use Program, and/or the Attending Veterinarian any injuries to or illnesses of the animals.
    13. The investigator/instructor will report promptly to the IACUC any non-compliance with the requirements of this Policy or the determinations of the IACUC.
    14. To facilitate the review of research and instructional protocols involving the use of vertebrate animals, the investigator/instructor is expected to attend IACUC meetings when requested by the IACUC.
    15. To facilitate the review of research and instructional protocols involving the use of vertebrate animals, the investigator/instructor may request a meeting with the IACUC. Requests should be submitted to the Chair of the IACUC.
  6. Responsibilities of the Department Chair or Cognizant Administrators
    1. Department Chairs (or cognizant administrators) will review and approve applications for use of vertebrate animals in research and instruction prior to their submission to the Office of Research and Sponsored Projects for consideration by the IACUC.
    2. Department Chairs (or cognizant administrators), through appropriate procedures established within their respective departments/units, will review research protocols for ethical considerations and for scientific and/or educational merit.
    3. In conjunction with the investigator/instructor, Department Chairs (or cognizant administrators) will report promptly to the IACUC any serious or continuing non-compliance with the requirements of this policy or the determinations of the IACUC.
    4. To facilitate the review of research and instructional protocols involving the use of vertebrate animals, Department Chairs (or cognizant administrators) are expected to attend IACUC meetings when requested by the IACUC.
  7. The University’s Institutional Animal Care and Use Program (IACUP)
    1. Responsibility for the University’s Institutional Animal Care and Use Program (IACUP) rests with the Office of the Provost. Day-to-day management of the program is the responsibility of the Director of the IACUP, who reports to the Provost. The IACUP was established to assure compliance with applicable standards, laws and regulations for humane treatment of animals used in research and instruction, to provide professional expertise and services to the University in matters concerning the care and use of vertebrate animals, and to facilitate implementation of this Policy.
    2. The responsibilities and authority of the Director of the Institutional Animal Care and Use Program include:
      1. Supervising the operation of all animal facilities, including direct supervision of animal care staff and provision of all animal care.
      2. Interpreting Federal and state laws, regulations, policies and guidelines concerning the utilization of animals in research and teaching activities.
      3. Developing and documenting all procedures and working policies pertaining to the animal care and use program and facility management.
      4. Coordinating and monitoring all vertebrate animal procurement and ensuring that appropriate permits and transportation arrangements are completed properly.
      5. Maintaining an information resource center pertaining to the utilization of animals.
      6. Providing information and services to investigators regarding requirements and procedures necessary to achieve a level of animal care and use that meets or exceeds contemporary professional standards and Federal and state regulations.
      7. Sponsoring and coordinating seminars and training programs for campus faculty, staff, and students on topics of appropriate animal utilization and care as required by Federal law.
      8. Providing a consulting service to investigators on matters of animal research, including housing; appropriate methods of handling and restraint; selection of analgesics, anesthetics, and tranquilizers; and methods of euthanasia.
      9. Monitoring and providing recommendations on all aspects of surgery programs, including preoperative procedures, surgical techniques, and postoperative care.
      10. Ensuring that appropriate monitoring programs are implemented to detect and treat ill or injured animals.
      11. Providing or otherwise ensuring the provision of veterinary care services to University-owned and/or -housed animals.
      12. Ensuring that the Attending Veterinarian is contacted whenever it appears that veterinary services are necessary.
      13. Making independent emergency decisions concerning the treatment regimen of individual animals found to be experiencing unalleviated pain or suffering, and ensuring that these animals are provided appropriate veterinary care or are humanely euthanized, unless this is in direct conflict with experimental goals that have been previously described in a protocol approved by the IACUC. (Whenever possible, the investigator will be consulted prior to initiating treatment or euthanasia. In all cases, however, the welfare of the animal will be the primary consideration.)
      14. Suspending activities that do not comply with this policy until they can be reviewed by the IACUC.
      15. Immediately reporting suspended activities to the Provost, the Director of Research and Sponsored Projects, and the Chair of the IACUC for resolution.
      16. Serving as a consultant to the IACUC.
      17. Coordinating semiannual inspections of animal facilities by the IACUC.
      18. Hosting and escorting persons inspecting the animal facilities (e.g., U.S. Department of Agriculture inspectors).
      19. Developing and submitting annual plans and budget requests for the Animal Care and Use Program to the Director of Research and Sponsored Projects.
      20. Preparing annual reports, Letters of Assurance, and Applications for Registration as required by the USDA and PHS.
      21. Acting as a liaison between faculty, university administrators, the IACUC and regulatory and funding agencies concerning animal welfare and use activities.

V. RELEVANT FORMS/LINKS

VI. QUESTIONS/RESPONSIBLE OFFICE

The responsible office for this Policy is the Provost/Vice President for Academic Affairs. For questions about this Policy, contact the Office of Sponsored Programs, Agreements, Research, and Contracts (SPARC).

VII. POLICY ADOPTION AND AMENDMENT DATES

Date Approved: June 25, 2004

Amended: N/A